Lagolax

Constipation

Origines

Constipation is a common digestive disorder that affects many people at different times in their lives. Here is a summary of the main causes and characteristics of constipation:

Definition

Constipation is characterised by bowel movements that are less frequent than normal (less than three times a week), difficulty passing stools or hard, dry stools. It may be occasional or chronic.

Main causes

• Insufficient fibre in the diet: Fibre helps to build stool volume and make it easier to pass. A diet low in fibre can therefore lead to constipation.

• Lack of fluids: Not drinking enough water can make stools hard and difficult to pass.

• Lack of exercise: Physical activity helps stimulate intestinal activity. Inactivity can therefore contribute to constipation.

• Ignoring the need to go to the toilet: Regularly holding off the urge to have a bowel movement can make constipation more likely.

• Changes in routine or lifestyle: For example, travel, changes in working hours, or other disruptions can affect the regular functioning of the intestines.

• Medications: Certain medications, particularly opioid analgesics, certain anticonvulsants and iron supplements, can cause or aggravate constipation.

• Medical conditions: Conditions such as diabetes, hypothyroidism or neurological disorders can affect bowel function.

• Stress and mental health: Stress and psychological problems can also influence digestion and intestinal activity.

Benefits

Macrogol, also known as polyethylene glycol (PEG), is a type of osmotic laxative frequently used to treat constipation. It is often combined with electrolytes to help maintain the body's electrolyte balance during treatment. Here's an overview of the main benefits of this combination in the treatment of constipation:

1. Effective in treating constipation

Macrogol draws water into the stool, making it softer and easier to pass. This can help relieve constipation effectively, including chronic constipation.

2. Preventing dehydration

The addition of electrolytes (sodium, potassium, chloride, bicarbonate) helps to prevent electrolyte imbalances that may occur as a result of increased water in the intestines, which is particularly important when using osmotic laxatives such as macrogol.

3. Safety in use

Macrogol is generally considered safe for most people, including long-term use under medical supervision. It is not addictive and does not alter normal intestinal function.

4. Ease of use

The treatment is often available as a powder to be dissolved in water, making it easy to administer and the dose can be adjusted to suit individual needs.

5. Use in various patient groups

It can be used in adults, including the elderly, and is often considered an option for children in cases of chronic constipation, under medical supervision.

6. Few side effects

Macrogol with electrolytes generally has few side effects. The most common are mild gastrointestinal symptoms such as bloating, gas or abdominal cramps.

7. Versatility

It can be used for intestinal preparation prior to certain medical or surgical procedures, in addition to its use for constipation.

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However, although macrogol is generally well tolerated, it is important to use it in accordance with the recommendations of a healthcare professional to avoid potential side effects and ensure that it is appropriate for the patient's specific situation.

Mechanism

Macrogol (polyethylene glycol) acts as an osmotic laxative, which means it works by retaining water in the stools. Here's a more detailed, step-by-step explanation of its mechanism of action:

• Water absorption: Macrogol is a large molecule that is not absorbed by the intestine. When ingested, it passes through the digestive system.

• Osmosis: As macrogol cannot be absorbed, it attracts and retains water in the colon through a process called osmosis. This increases the volume of water in the intestine.

• Increased stool volume: The water retained by macrogol increases the volume and water content of stools, making them softer and bulkier.

• Stimulation of peristalsis: The increased volume of stool stimulates the intestinal muscles to contract (peristalsis), which helps push the stool outwards.

• ÉEasier emptying: softer, bulkier stools are easier to pass, which relieves constipation.

Side effects

1. Occasionally, gastrointestinal problems may appear, with borborygma, abdominal pain, nausea and mild diarrhoea (especially at the beginning).

2. Rarely, hypersensitivity reactions (rush, urticaria) may occur. Consult your doctor or pharmacist if you experience any side effects, even if they are not mentioned. If the symptoms persist, consult your doctor. If you forget to take a dose, do not take a double dose, but wait and take the next one.

But even when the tolerance of a product is considered to be excellent, it is advisable to seek the advice of a health professional, especially if the condition is recurrent or arises in specific situations.

Conclusion

Lagolax is a good preparation for treating chronic constipation. It has been well documented in numerous studies.

The medicine should be used in accordance with the recommendations given in the package leaflet, at the dosages defined according to age.

 

Health professionals are well acquainted with macrogol and their advice will be invaluable if you have any doubts or are unsure of its effectiveness.